Team Science Projects

We are combining longitudinal in vivo calcium imaging with spatial transcriptomics to investigate how specific cell types restructure their activity during novelty processing and task learning.

We are studying task-switching behaviors in mice to determine how the brain controls the flow of its own activity and how neuronal circuits are reconfigured to dynamically route information for different tasks.

OpenScope provides access to cutting-edge neurophysiological methods to scientists across the world. Similar to astronomical observatories, scientists propose experiments that are then executed at the Allen Institute.

Our goal is to investigate the computations performed by individual neurons, based on measuring synaptic input and firing output. We are developing technologies with single synapse resolution in the living brain. New microscopes allow tracking synaptic activity across the entire dendritic arbor.

We are studying the molecular and anatomical subclasses of neuromodulator neurons and exploring how networks use neuromodulators to drive learning and decision making.

We are using optical connection-mapping techniques and brain computer interface (BCI) in the context of a learning task to ask how the brain updates its synapses to support behavioral learning without interfering with existing skills or memories.