Open Tool

Genetic Tools Atlas

Description

The Genetic Tools Atlas (GTA) is a searchable web tool representing information and data on enhancer-adeno-associated viruses (enhancer AAVs) and mouse transgenes developed and tested at the Allen Institute for Brain Science. The GTA offers a large genetic toolkit for selective gene expression in brain cell types of interest.

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Platforms accelerate our work

Surgery

This team performs a variety of surgical procedures, including stereotaxic injections and implanting chronic cranial windows and Neuropixels probes.

Multi-Neuropixels Electrophysiology

This platform implements pioneering technology for highly reproducible, targeted, brain-wide, cell-type-specific electrophysiology to record neural activity from defined neuron types across the brain. Analysis and quality control of the electrophysiology data are fully automated.

Brain-Wide Anatomy at Cellular Resolution

This platform combines innovative histology, microscopy, image handling, and machine learning to map the morphology and molecular identity of individual neurons across the whole brain at high throughput.

Fiber Photometry

This platform enables optical measurement of neural activity and neurotransmitter release in populations of neurons to study neural circuit dynamics in behaving animals.

Behavior

The Behavior platform uses advanced technology to implement a standardized, modular, multi-task virtual reality gymnasium for mice, with the goal to study brain function across different behaviors at scale.