Date
12.7.2025 -
Location
,
Workshop

NeurIPS Workshop

Description

Join us at the Data on the Brain & Mind Workshop at NeurIPS 2025. This event is focused on applications of AI to neuroscience. We will be presenting a tutorial on accessing and using the Allen Brain Observatory Visual Behavior Neuropixels dataset. This dataset consists of dense electrophysiological recordings of neural activity in mice performing a visual change detection task. Each experiment includes data from up to six Neuropixels probes recording simultaneously in cortex, hippocampus, thalamus and midbrain, while mice were exposed to different sensory and behavioral contexts, including familiar and novel stimuli, as well as active and passive stimulus blocks. See An Overview of the Neuropixels Visual Behavior Dataset From the Allen Institute for a tutorial on analyzing the Visual Behavior Neuropixels dataset from the Allen Institute.

Platforms accelerate our work

Mesoscale Anatomy

This platform builds on turn-key lightsheet microscopes to image mouse brains at high resolution and throughput. Analysis of the resulting volumetric images, including registration to standard brain coordinates and segmentation and counting of individual neurons, is fully automated.

SLAP2

This platform uses a two-photon microscope SLAP2 that records patterns of synaptic input and output in individual neurons at hundreds to thousands of frames per second in mice performing complex behaviors, using a flexible scan system that combines a digital micromirror device (DMD) with a high-speed scanner.

Scientific Instrumentation & Process Engineering

The Scientific Instrumentation and Process Engineering (SIPE) team is a shared engineering resource within the Allen Institute, focused on enabling and scaling cutting-edge bioscience through integrated hardware and software systems.

Surgery

This team performs a variety of surgical procedures, including stereotaxic injections and implanting chronic cranial windows and Neuropixels probes.

Multi-Neuropixels Electrophysiology

This platform implements pioneering technology for highly reproducible, targeted, brain-wide, cell-type-specific electrophysiology to record neural activity from defined neuron types across the brain. Analysis and quality control of the electrophysiology data are fully automated.

Brain-Wide Anatomy at Synaptic Resolution

This platform combines innovative histology, ExA-SPIM microscopy, image handling, and machine learning to map the morphology and molecular identity of individual neurons across the whole brain at high throughput.

Fiber Photometry

This platform enables optical measurement of neural activity and neurotransmitter release in populations of neurons to study neural circuit dynamics in behaving animals.

Behavior

The Behavior platform uses advanced technology to implement a standardized, modular, multi-task virtual reality gymnasium for mice, with the goal to study brain function across different behaviors at scale.